Khnayzer, Rony S.; Abi-Habib, Ralph; El-Sibai, Mirvat; Azar, Daniel F.; Farhat, Stephanie; Audi, Hassib; SAS; 200501196; 200901419; 200703859; Natural Sciences; rony.khnayzer@lau.edu.lb; ralph.abihabib@lau.edu.lb; mirvat.elsibai@lau.edu.lb; Lebanese American University
Abstract:
A photochemically dissociating ligand in Ru(bpy)2(dmphen)Cl2 [bpy = 2,2′-bipyridine; dmphen = 2,9-dimethyl-1,10-phenanthroline] was found to be more cytotoxic on the ML-2 Acute Myeloid Leukemia cell line than Ru(bpy)2(H2O)22+ and prototypical cisplatin. Our findings illustrate the potential potency of diimine ligands in photoactivatable Ru(II) complexes.
Citation:
Azar, D. F., Audi, H., Farhat, S., El-Sibai, M., Abi-Habib, R. J., & Khnayzer, R. S. (2017). Phototoxicity of strained Ru (ii) complexes: is it the metal complex or the dissociating ligand?. Dalton Transactions, 46(35), 11529-11532.
