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SOM - Scholarly Publications: Recent submissions

  • Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus 
    Bahous, Sola Aoun; Safar, Michel E.; Gnakaméné, Jean-Barthélémy; Yannoutsos, Alexandra; Thomas, Frédérique
    Despite adequate glycemic and blood pressure control, treated type 2 diabetic hypertensive subjects have a significantly elevated overall/cardiovascular risk. We studied 244 816 normotensive and 99 720 hypertensive subjects ...
  • Renal Function Decline in Recipients and Donors of Kidney Grafts 
    Bahous, Sola Aoun; Khairallah, Maya; Al Danaf, Jad; Halaby, Rim; Korjian, Serge; Daaboul, Yazan; Salameh, Pascale; Stephan, Antoine; Blacher, Jacques; Safar, Michel E.
    Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. In recipients and donors of kidney grafts, renal function decline may be linked differently to ...
  • Arterial stiffness and renal transplantation 
    Bahous, Sola Aoun; Safar, Michel E.; Delahousse, Michel
  • Change in Pulse Wave Velocity and Short‐Term Development of Cardiovascular Events in the Hemodialysis Population 
    Bahous, Sola Aoun; Korjian, Serge; Daaboul, Yazan; El-Ghoul, Balsam; Samad, Salam; Salameh, Pascale; Dahdah, Georges; Hariri, Essa; Mansour, Anthony; Spielman, Kathryn; Blacher, Jacques; Safar, Michel E.
    The association between single measurements of carotid‐femoral pulse wave velocity (cfPWV) and cardiovascular (CV) events is driven by late events beyond 12 months of follow‐up. This prospective study compares single ...
  • Aortic Stiffness, Kidney Disease, and Renal Transplantation 
    Bahous, Sola Aoun; Blacher, Jacques; Safar, Michel E.
    In subjects with chronic kidney disease (CKD), treatment of high systolic blood pressure is a key element in preventing disease progression and the occurrence of cardiovascular (CV) events. This relationship between the ...
  • Aortic pulse wave velocity in renal transplant patients 
    Bahous, Sola Aoun; Stephan, Antoine; Barakat, Wadad; Blacher, Jacques; Asmar, Roland; Safar, Michel E.
    In subjects with end-stage renal disease (ESRD) undergoing hemodialysis, aortic pulse wave velocity (PWV) is increased independently of blood pressure level and mostly is a strong predictor of cardiovascular risk. Few ...
  • HIV associated pulmonary emphysema 
    Diab, K.; Petrache, I.; Twigg, H. L.; Stephens, R. S.; Flores, S.; Tuder, R. M.
    Chronic lung diseases are increasingly recognised complications of the human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). Of these, pulmonary emphysema, characterised by permanent ...
  • A 46-year-old man with dyspnea and left diaphragm paralysis 
    Diab, Khalil; Snook, Riley J.; Farber, Mark
    A 46-year-old man was referred because of increasing shortness of breath. His symptoms started 1 year prior after he fell while working in Iraq as a contractor. Progressively increasing shortness of breath developed on ...
  • A 62-year-old man with hypotension and a large chest fluid collection 
    Diab, Khalil; Wolf, Karen M.
    A 62-year-old man was admitted with increased shortness of breath and a cough associated with yellowish sputum production. His symptoms had been progressively worsening over weeks. Pertinent symptoms at presentation included ...
  • Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema 
    Diab, Khalil J.; Adamowicz, Jeremy J.; Kamocki, Krysztof; Rush, Natalia I.; Garrison, Jana; Gu, Yan; Schweitzer, Kelly S.
    Rationale: Vascular endothelial growth factor receptor (VEGFR) inhibition increases ceramides in lung structural cells of the alveolus, initiating apoptosis and alveolar destruction morphologically resembling emphysema. ...
  • An 81-Year-Old Man With Lactic Acidosis, Refractory Hypoglycemia, and Lymphocytosis 
    Diab, Khalil; Knox, Kenneth S.; Hage, Chadi A.
    An 81-year-old man was admitted to our hospital for refractory hypoglycemia, metabolic acidosis, unexplained lymphocytosis, and significant weight loss. The patient was known to have non–insulin-dependent diabetes mellitus, ...
  • A 75-year-old female with hemoptysis and recurrent respiratory infections 
    Diab, Khalil; Baker, Mary S.
    This paper describes the case of a 75-year-old female who presented with significant hemoptysis over a 7–10 day period. She had a history of a left lower lobectomy 10 years prior for a “lung abscess.” She subsequently had ...
  • A patient with severe hypoxia secondary to a large iatrogenic pulmonary artery to pulmonary vein fistula 
    Diab, Khalil; Cucci, Anthony; Kukreja, Sandeep; Gupta, Rajat
    Pulmonary arteriovenous malformations are uncommon communications between the pulmonary arteries and veins, most commonly associated with hereditary haemorrhagic telangiectasia. They can also be associated with a variety ...
  • Pneumomediastinum and pneumoperitoneum caused by tracheostomy displacement 
    Diab, Khalil; Jana, Muhammad Y.; Kniese, Christopher M.
  • Intrapulmonary Recombinant Factor VII as an Effective Treatment for Diffuse Alveolar Hemorrhage 
    Diab, Khalil J.; Baker, Mary S.; Carlos, W. Graham; Mathur, Praveen
    Background: The diffuse alveolar hemorrhage (DAH) syndrome is a life-threatening pulmonary complication related to systemic vasculitides, posthematopoietic stem cell transplantation, drugs, or toxins. Once DAH develops, ...
  • Reduction of laboratory utilization in the intensive care unit 
    Diab, Khalil; Eliott, Rachel; Raad, Samih; Dickerson, Evan
    Objective: In our academic intensive care unit (ICU), there is excess ordering of routine laboratory tests. This is partially due to a lack of transparency of laboratory-processing costs and to the admission order plans ...
  • Undetected lymph node metastases in presumed early stage NSCLC SABR patients 
    Diab, Khalil; Cerra-Franco, Alberto; Lautenschlaeger, Tim
    Introduction: Stereotactic body radiation therapy (SBRT, also called stereotactic ablative body radiation SABR) is the treatment of choice for many patients with early-stage non-small cell lung cancer (NSCLC), including ...
  • COPD 
    Diab, Khalil J.; Salman, Zafirah; Nobari, Matthew M.; Tybor, David; Khan, Babar A.
    The annual cost of chronic obstructive pulmonary disease (COPD) in the United States in 2008 was $53.7 billion, largely due to visits to a medical facility for exacerbations. In this article, we explore the most recent ...
  • Indwelling pleural catheters in hepatic hydrothorax 
    Diab, Khalil; Kniese, Christopher; Ghabril, Marwan; Bosslet, Gabriel; SOM; 201900605; N/A; khalil.diab@lau.edu.lb; Lebanese American University
    Background Treatment of hepatic hydrothorax (HH) generally involves sodium restriction, diuretics, and serial thoracentesis. In more advanced cases, transjugular intrahepatic portosystemic shunt and liver transplantation ...
  • Macrophage activation syndrome in a patient with systemic-onset juvenile idiopathic arthritis initially treated for atypical Kawasaki disease 
    Wakim, Gerard; Hachem, Ahmad; Naja, Ahmad; Demachkieh, Rawan; Hariri, Essa
    Systemic-onset juvenile idiopathic arthritis (SoJIA) is the most common rheumatic disorder in children and its presentation can mimic atypical Kawasaki disease. The diagnosis of SoJIA is often challenging and children are ...

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