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SOP - Scholarly Publications: Recent submissions

  • Salvia libanotica improves glycemia and serum lipid profile in rats fed a high fat diet 
    Bassil, Maya; Daher, Costantine F.; Mroueh, Mohammad; Zeeni, Nadine; SAS; SOP; 201102356; 199190130; 199590020; 201000400; Natural Sciences; mbassil@lau.edu.lb; cdaher@lau.edu.lb; mmroueh@lau.edu.lb; nadine.zeeni@lau.edu.lb (2016-04-21)
    Background Salvia libanotica (S. Libanotica) is a commonly used herb in folk medicine in Lebanon and the Middle East. The present study aimed to assess the scientific basis for the therapeutic use of S. libanotica in ...
  • Synthesis of some new amide-linked bipyrazoles and their evaluation as anti-inflammatory and analgesic agents 
    Faour, Wissam H.; Mroueh, Mohamed; Daher, Costantine F.; Elbayaa, Rasha Y.; Ragab, Hanan M.; Ghoneim, Asser I.; El-mallah, Ahmed I.; Ashour, Hayam M. A..; SAS; SOM; SOP; 200904962; 199590020; 199190130; Natural Sciences; wissam.faour@lau.edu.lb; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2016-04-21)
    Four series of new bipyrazoles comprising the N-phenylpyrazole scaffold linked to polysubstituted pyrazoles or to antipyrine moiety through different amide linkages were synthesized. The synthesized compounds were evaluated ...
  • Association of coronary artery disease and chronic kidney disease in Lebanese population 
    Milane, Aline; Khazen, Georges; Salloum, Angelique K.; Zalloua, Pierre; Ghassibe-Sabbagh, Michella; Zeineddine, Nabil; Masri, Leila; El Bayeh, Hamid; SAS; SOP; 200904164; 200703831; 201105253; Computer Science and Mathematics; aline.milane@lau.edu.lb; GKhazen@lau.edu.lb; angelique.salloum@lau.edu.lb; pierre.zalloua@lau.edu.lb (2016-03-17)
    Background: More evidence is emerging on the strong association between chronic kidney disease (CKD) and cardiovascular disease. We assessed the relationship between coronary artery disease (CAD) and renal dysfunction level ...
  • Cancer cell resistance mechanisms 
    El-Sibai, M.; Abou-Antoun, T.; Al-Dimassi, S.; SAS; SOP; 200703859; 201005279; Natural Sciences; mirvat.elsibai@lau.edu.lb; tamara.abouantoun@lau.edu.lb (2015-12-18)
    Cancer is a leading cause of death worldwide accounting to 13 % of all deaths. One of the main causes behind the failure of treatment is the development of various therapy resistance mechanisms by the cancer cells leading ...
  • Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways 
    Mroueh, Mohamad; Taleb, Robin I.; El-Sibai, Mirvat; Daher, Costantine F.; Mansour, Anthony; Bodman-Smith, K.B.; Shehaby, Wassim N.; SOP; SAS; 199590020; 200901968; 200703859; 199190130; Natural Sciences; mmroueh@lau.edu.lb; robin.taleb@lau.edu.lb; mirvat.elsibai@lau.edu.lb; cdaher@lau.edu.lb (2015-12-17)
    Daucus carota L. ssp. carota (Apiacea, wild carrot, Queen Anne's lace) has been used in folk medicine throughout the world and recently was shown to possess anticancer and antioxidant activities. This study aims to determine ...
  • ALOX5AP gene variants show differential association with coronary artery disease in different populations 
    El-Sibai, Mirvat; Deeb, Mary E.; Khazen, Georges; Zreik, Tony G.; El Bayeh, Hamid; Zalloua, Pierre A.; Alwan, Ahmad; Platt, Daniel E.; Saade, Stephanie; Youhanna, Sonia C.; Maalouf, Assaad; Abchee, Antoine; SAS; SOP; SOM; 200703859; 200900035; 201105253; 200802707; 200902679; 200300001; Natural Sciences; mirvat.elsibai@lau.edu.lb; mary.deeb@lau.edu.lb; GKhazen@lau.edu.lb; tgzreik@lau.edu.lb; hamid.elbayeh@lau.edu.lb; pierre.zalloua@lau.edu.lb (2015-12-17)
    Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. Previous reports correlating ALOX5AP gene variants and CAD showed conflicting results depending on the population ...
  • Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells 
    Mroueh, Mohammad; Taleb, Robin I.; Daher, Costantine F.; El-Sibai, Mirvat; Shebaby, Wassim N.; Bodman-Smith, Kikki; Mansour, Anthony; SAS; SOP; 199590020; 200901968; 199190130; 200703859; Natural Sciences; mmroueh@lau.edu.lb; robin.taleb@lau.edu.lb; cdaher@lau.edu.lb; mirvat.elsibai@lau.edu.lb (2015-12-16)
    Background Daucus carota L.ssp.carota (wild carrot), an herb used in folk medicine worldwide, was recently demonstrated to exhibit anticancer activity. In this study we examined the anticancer effect of Daucus carota oil ...
  • Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract 
    El-Sibai, Mirvat; Daher, Costantine F.; Mroueh, Mohamad; Tenkerian, Clara; SAS; SOP; 200703859; 199190130; 199590020; Natural Sciences; mirvat.elsibai@lau.edu.lb; cdaher@lau.edu.lb; mmroueh@lau.edu.lb (2015-12-16)
    Tragopogon porrifolius (Asteraceae), commonly referred to as white salsify, is an edible herb used in Lebanese folk medicine to treat cancer and liver dysfunction. In this study, we investigated the antioxidant activity ...
  • Antioxidant and hepatoprotective activities of the oil fractions from wild carrot (Daucus carota ssp. carota) 
    Daher, Costantine F.; El-Sibai, Mirvat; Mroueh, Mohamad; Shebaby, Wassim N.; Bodman-Smith, Kikki; Mansour, Anthony; Karam, Marc C.; SAS; SOP; 199190130; 200703859; 199590020; Natural Sciences; cdaher@lau.edu.lb; mirvat.elsibai@lau.edu.lb; mmroueh@lau.edu.lb (2015-12-16)
    Context: Wild carrot, Daucus carota L. ssp. carota (Apiacae), is widely distributed throughout the world and has various uses in traditional medicine in Lebanon. Objective: The present study aimed to fractionate and ...
  • Magnetic property, DFT calculation, and biological activity of bis[(μ2-chloro)chloro(1,10-phenanthroline)copper(II)] complex 
    Mroueh, Mohamad; Daher, Costantine; Hariri, Essa; Demirdjian, Sally; Isber, Samih; Choi, Eun Sang; Mirtamizdoust, Babak; Hammud, Hassan H.; SAS; SOP; 199190130; 199590020; Natural Sciences; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2015-12-16)
    The dinuclear complex bis[(μ2-chloro)chloro(1,10-phenanthroline)copper(II)] (1) was synthesized, and characterized by X-ray, FTIR and thermal analysis. The fitting of magnetic susceptibility and magnetization curve of (1) ...
  • Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats 
    Zeeni, Nadine; Daher, Costantine F.; Mroueh, Mohamad; Saab, Lea; SAS; 199190130; 201000400; 199590020; Natural Sciences; nadine.zeeni@lau.edu.lb; cdaher@lau.edu.lb; mmroueh@lau.edu.lb (2015-12-15)
    Tragopogon porrifolius (white salsify) is an edible plant commonly used in folk medicine in Lebanon and neighbouring countries. This study investigates the effect of the aqueous extract of the aerial part of T. porrifolius ...
  • Prophylaxis with Ertapenem in Patients with Obstructive Jaundice Undergoing Endoscopic Retrograde Cholangiopancreatography 
    Mroueh, Mohamad; Sharara, Ala I.; El Hajj, Ihab I.; Kyriacos, Soula Boustani; Abdul-Baki, Heitham; Chaar, Hani F.; Aoun, Elie; Hashash, Jana G.; Mansour, Nabil M.; Kanj, Souha S.; SOP; 199590020; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb (2015-12-01)
    BACKGROUND: Cholangitis and biliary sepsis are rare but serious complications of endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study is to investigate the safety, efficacy, and biliary penetration ...
  • The role of methanolic extract of Quercus infectoria bark in lipemia, glycemia, gastric ulcer and bacterial growth 
    Mroueh, Mohamad; Daher, Costantine F.; Khouzami, L.; SOP; 199590020; 199190130; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2015-12-01)
    Nowadays, the surge of consumption of herbal supplements is encouraged by several factors, including the common belief that all herbal products are relatively safe and effective. The present investigation explores the ...
  • Chemopreventive effects of wild carrot oil against 7,12-dimethyl benz(a)anthracene-induced squamous cell carcinoma in mice 
    Mroueh, Mohamad; Daher, Costantine F.; Abu Zeinab, Rami; Diab-Assaf, Mona; Jurjus, Abdo; Wex, Brigitte; Sakr, Amer; SOP; SAS; 199590020; 199190130; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2015-12-01)
    Context: Daucus carota L. ssp. carota (Apiacea) is widely distributed throughout the world and has many uses in traditional medicine. Objective: The present study investigates the chemopreventive effects of oil extract ...
  • Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon 
    Mroueh, Mohamad; Daher, Costantine F.; Hage-Sleiman, Rouba; SOP; SAS; 199590020; 199190130; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2015-12-01)
    Context: Althaea officinalis Linn. (Malvaideae) flower is commonly used in folk medicine in Lebanon and neighboring countries. Although most of the studies have been conducted on the mucilage-rich roots, little is known ...
  • Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells 
    Mroueh, Mohamad; Daher, Costantine F.; Abi-Habib, Ralph J.; Bekdash, Amira; Tawil, Mirna; SAS; SOP; 199590020; 199190130; 200901419; Natural Sciences; mmroueh@lau.edu.lb; cdaher@lau.edu.lb; ralph.abihabib@lau.edu.lb (2015-12-01)
    In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. Analysis of ...
  • In Vitro Testing of Ciprofloxacin Formulations and Preliminary Study on BCS Biowaiver 
    Mroueh, Mohamad; Kyriacos, Soula Boustani; Boukarim, Chawki; Safi, William; Maroon, Aline Bou; El-Khoury, Ghada; Shehayeb, Rabih; SOP; 199590020; 200104046; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb; ghada.khoury@lau.edu.lb (2015-11-25)
    The purpose of this study was to compare the technical quality of ciprofloxacin tablets and examine the feasibility of biopharmaceutical classification system (BCS) biowaiver. Ciprofloxacin is a synthetic quinolone ...
  • Levels of benzoic and sorbic acid preservatives in commercially produced yoghurt in Lebanon 
    Mroueh, Mohamad; Issa, Dina; Khawand, Jesele; Haraty, Bassam; Malek, Amal; Kassaify, Zeina; Toufeili, Imad; SOP; 199590020; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb (2015-11-25)
    Benzoic and sorbic acids and their salts are extensively used in the preservation of foods. Their levels of use in different food products are regulated by national and international regulatory agencies. Benzoic acid ...
  • The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats 
    Mroueh, Mohamad; Daher, Costantine F.; Wehbe, Katia; SOP; SAS; 199590020; 199190130; Pharmaceutical Sciences Department; mmroueh@lau.edu.lb; cdaher@lau.edu.lb (2015-11-25)
    Daucus carota (DC) is among commonly used plants in folk medicine in Lebanon and the region. The present investigation was undertaken to examine the effects of the aqueous and extracts of Daucus carota umbels against acute ...
  • Evaluation of Heavy metals content in dietary supplements in Lebanon 
    Korfali, Samira Ibrahim; Hawi, Tamer; Mroueh, Mohamad; SAS; 197829160; Natural Sciences; skorfali@lau.edu.lb; mmroueh@lau.edu.lb; 199590020 (2015-11-07)
    Background: The consumption of dietary supplements is widely spread and on the rise. These dietary supplements are generally used without prescriptions, proper counseling or any awareness of their health risk. The current ...

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