Retrotrapezoid (RTN) neurons sustain breathing automaticity. These neurons have chemoreceptor properties but their firing is also regulated by multiple synaptic inputs of uncertain function. Here we test whether RTN, like ...

In conscious mammals, hypoxia or hypercapnia stimulates breathing while theoretically exerting opposite effects on central respiratory chemoreceptors (CRCs). We tested this theory by examining how hypoxia and hypercapnia ...

Combined optogenetic activation of the retrotrapezoid nucleus (RTN; a CO2/proton-activated brainstem nucleus) with nearby catecholaminergic neurons (C1 and A5), or selective C1 neuron stimulation, increases blood pressure ...

Le baroréflexe artériel, et plus particulièrement sa composante sympathique, pourrait limiter les effets hypertenseurs du stress émotionnel. Il a cependant été proposé que ce type de stress inhibe, voire abolit, le ...

C1 neurons activate sympathetic tone and stimulate the hypothalamic–pituitary–adrenal axis in circumstances such as pain, hypoxia or hypotension. They also innervatepontine noradrenergic cell groups, including the locus ...

This study compared the baroreflex control of lumbar and renal sympathetic nerve activity (SNA) in conscious rats. Arterial pressure (AP) and lumbar and renal SNA were simultaneously recorded in six freely behaving rats. ...

The present study examined whether the gain of the transfer function relating cardiac-related rhythm of renal sympathetic nerve activity (RSNA) to arterial pressure (AP) pulse might serve as a spontaneous index of sympathetic ...

We used optogenetics to determine the global respiratory effects produced by selectively stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test whether these neurons detect changes in the ...

In this review, we examine why blood pressure (BP) and sympathetic nerve activity (SNA) increase during a rise in central nervous system (CNS) Pco2 (central chemoreceptor stimulation). CNS acidification modifies SNA by two ...