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SoAS - Scholarly Publications: Recent submissions

  • Lebanese militias 
    Rowayheb, Marwan; SAS; 198832390; Social Sciences; marwan.rowayheb@lau.edu.lb (2016-01-18)
  • The Comic Disruption of Stereotypes in Loubna Haikal's "Seducing Mr. Maclean 
    Balaa, Luma; SAS; 200402871; English; luma.balaa@lau.edu.lb (2016-01-15)
  • Children’s Responses to Hoodwinked, the movie 
    Balaa, Luma; SAS; 200402871; English; luma.balaa@lau.edu.lb (2016-01-15)
    Children nowadays live in a digital multi-media age and are exposed to new and cross media children’s literature with integrated experiences such as films, video, DVDs, Internet, cable TV or video games. Some educators ...
  • Developing and piloting a framework for studying the alignment of mathematics examinations with the curriculum 
    Osta, Iman; SAS; 199329170; Education; iman.osta@lau.edu.lb (2016-01-14)
    This research aimed at developing a methodological framework to investigate the alignment of the Lebanese national math exam tests with the curriculum at the middle school level, during the transitory period of a major ...
  • Students’ Alternative Conceptions about Electricity and Effect of Inquiry-Based Teaching Strategies 
    Osta, Iman; Chatila Afra, Nada; Zoubeir, Wassim; SAS; 199329170; Education; iman.osta@lau.edu.lb (2016-01-14)
    This study attempted to investigate the alternative conceptions that a group of 12 Lebanese students in a grade 9 class hold about electricity. It also attempted to evaluate learning outcomes of implementing in that class ...
  • Description and Evaluation of the Information Literacy Program in a Private School in Lebanon 
    Osta, Iman; Nabhani, Mona; Sakr, Rola; SAS; 199329170; 198129610; Education; iman.osta@lau.edu.lb; mnabhani@lau.edu.lb (2016-01-14)
    The purpose of this study was to describe the information literacy program offered through the library of a private elementary school in Beirut, to evaluate its effectiveness, and to formulate recommendations for improving ...
  • Teaching Methods as Reflected by Course Syllab of Teacher Preparation Programs in Some of the Major Universities in Lebanon 
    Osta, Iman; SAS; 199329170; Education; iman.osta@lau.edu.lb (2016-01-14)
    This paper investigates the teaching methods used within the Teacher Preparation Programs (TPPs) in 12 Lebanese universities. The “document analysis” research method is used to analyze the collected documents: seven ...
  • A tandem metathesis–hydrogenation route to dicarba analogues of cystine-containing cyclic peptides 
    Elaridi, Jomana; Whelan, Amanda N.; Harte, Michael; Smith, Suzanne V.; Jackson, W. Roy; Robinson, Andrea J.; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    Dicarba cyclic peptide analogues of the cyclic peptide octreotide have been synthesised in good yields using a single pot, on resin, tandem homogeneous metal-catalysed metathesis–hydrogenation sequence.
  • A catalytic asymmetric synthesis of 5,5-dimethylproline 
    Elaridi, Jomana; Jackson, W. Roy; Robinson, Andrea J.; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    The methyl ester derivative of commercially available N-acetyl-allylglycine readily undergoes cross-metathesis with 2-methylbut-2-ene and ruthenium–alkylidene catalyst to afford the prenylglycine derivative. Acid-catalysed ...
  • Metal-catalysed tandem metathesis-hydrogenation reactions for the synthesis of carba analogues of cyclic peptides 
    Elaridi, Jomana; Whelan, Amanda N.; Mudler, Roger J.; Robinson, Andrea J.; Jackson, W. Roy; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    Dicarba cyclic peptide analogues of the cystine-containing octapeptides octreotide, lanreotide, and vapreotide, all known somatostatin analogues, have been synthesized via an on-resin homogeneous metal-catalysed sequence ...
  • An enantioselective synthesis of β2-amino acid derivatives 
    Elaridi, Jomana; Thaqi, Ali; Prosser, Andrew; Jackson, W. Roy; Robinson, Andrea J.; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    Enantioselective hydrogenation of a series of (E)-α-substituted β-amidoacrylates using Rh(I)-catalysts with chiral phosphine ligands (BPE, DuPHOS) gives β2-amino acid derivatives with enantioselectivities of up to 67%. A ...
  • Microwave-assisted RCM for the synthesis of carbocyclic peptides 
    Elaridi, Jomana; Robinson, Andrea J.; Mujcinovic, Selma; Jackson, W. Roy; Van Lierop, Bianca J.; SAS; 201100947; Natural Sciences (2015-12-22)
    Microwave irradiation dramatically improves the efficiency of ring closing metathesis (RCM) reactions of resin-attached peptides and the technology is illustrated by the highly selective synthesis of dicarba analogues of ...
  • Metathesis assisted synthesis of cyclic peptides 
    Elaridi, Jomana; Xing Guo, Cheng; Garland, Rebecca; Ahmed, Aishath; Lierop, Bianca van; Illesingle, Jayamini; Jackson, W. Roy; Robinson, Andrea J.; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    Installation of reversible, metathesis-active tethers into linear peptide sequences can be used to promote formation of cyclic peptide amides and esters.
  • Regioselective formation of interlocked dicarba bridges in naturally occurring cyclic peptide toxins using olefin metathesis 
    Elaridi, Jomana; Robinson, Andrea J.; Van Lierop, Bianca J.; Garland, Rebecca D.; Teoh, Euneace; Illesingle, Jayamini P.; Jackson, W. Roy; SAS; 201100947; Natural Sciences; jomana.aridi@lau.edu.lb (2015-12-22)
    Bis-dicarba analogues of native dicystine-containing α-conotoxin Rg1A, an analgesic peptide isolated from cone snail venom, were constructed on resin using a regioselective metathesis–hydrogenation strategy.
  • StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion 
    Sobh, Rania; Nasser, Selim; El-Sibai, Mirvat; Hanna, Samer; Khalil, Bassem; Nasrallah, Anita; Saykali, Bechara A.; SAS; SOM; 200904866; 200804624; 200703859; Natural Sciences; rania.sobh@lau.edu.lb; selim.nasser@lau.edu.lb; mirvat.elsibai@lau.edu.lb (2015-12-18)
    Breast cancer is one of the most commonly diagnosed cancers in women around the world. In general, the more aggressive the tumor, the more rapidly it grows and the more likely it metastasizes. Members of the Rho subfamily ...
  • Cancer cell resistance mechanisms 
    El-Sibai, M.; Abou-Antoun, T.; Al-Dimassi, S.; SAS; SOP; 200703859; 201005279; Natural Sciences; mirvat.elsibai@lau.edu.lb; tamara.abouantoun@lau.edu.lb (2015-12-18)
    Cancer is a leading cause of death worldwide accounting to 13 % of all deaths. One of the main causes behind the failure of treatment is the development of various therapy resistance mechanisms by the cancer cells leading ...
  • Colorectal Cancer Causes and Treatments 
    El-Sibai, Mirvat; Nasrallah, Anita; SAS; 200703859; Natural Sciences; mirvat.elsibai@lau.edu.lb (2015-12-18)
    Colon cancer is the cancer of the epithelial cells lining the colon. This type of cancer occurs in many people that are either genetically predisposed or exposed to risk factors. Colorectal cancer is mainly divided into ...
  • Invadopodia, Regulation, and Assembly in Cancer Cell Invasion 
    El-Sibai, Mirvat; Saykali, Bechara A.; SAS; 200703859; Natural Sciences; mirvat.elsibai@lau.edu.lb (2015-12-18)
    The occurrence of invadopodia has been, since its characterization, a hallmark of cancerous cell invasion and metastasis. These structures are now the subject of a controversy concerning their cellular function, molecular ...
  • Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion 
    El-Sibai, Mirvat; Rizk, Sandra; Khoury, Nathalie; El-Hayek, Stephany; Tarras, Omayr; El Sabban, Marwan; SAS; 200703859; 199829370; Natural Sciences; mirvat.elsibai@lau.edu.lb; sandra.rizk@lau.edu.lb (2015-12-18)
    Kefir, a fermented milk product, exhibits anti‑tumoral activity in vivo; yet its mechanism of action remains elusive. Recent studies have focused on the mechanism of action of kefir on cancer cells in vitro. The current ...
  • Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways 
    Mroueh, Mohamad; Taleb, Robin I.; El-Sibai, Mirvat; Daher, Costantine F.; Mansour, Anthony; Bodman-Smith, K.B.; Shehaby, Wassim N.; SOP; SAS; 199590020; 200901968; 200703859; 199190130; Natural Sciences; mmroueh@lau.edu.lb; robin.taleb@lau.edu.lb; mirvat.elsibai@lau.edu.lb; cdaher@lau.edu.lb (2015-12-17)
    Daucus carota L. ssp. carota (Apiacea, wild carrot, Queen Anne's lace) has been used in folk medicine throughout the world and recently was shown to possess anticancer and antioxidant activities. This study aims to determine ...

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