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School of Arts and Sciences: Recent submissions

  • Vertical 'half-and-a-half'syndrome 
    Ahdab, Rechdi; Riachi, Naji
    The patient's behavioural impairment and right-sided ataxia improved significantly over the following week and the patient was discharged with residual anterograde amnesia, minimal word finding difficulties and vertical ...
  • Persistent multifocal pseudo‐conduction blocks in vasculitic neuropathy without antiganglioside antibodies 
    Ahdab, Rechdi; Michel, Marc; Neves, Danusa O.
    A woman presented with severe multifocal acute axonal neuropathy due to necrotizing vasculitis. Six years later, electrophysiological examination revealed features suggestive of persistent conduction block (CB) with increased ...
  • Mary Stuart, or, Tortured majesty 
    SAS; 199529020; English; kaercke@lau.edu.lb; Vondel, Joost van den; Lebanese American University (Dovehouse EditionsOttawa, )
  • The story of Sir Konrad Grünemberg's pilgrimage to the Holy Land in 1486 
    SAS; 199529020; English; kaercke@lau.edu.lb; Grünemberg, Konrad; Lebanese American University (Centro interuniversitario di ricerche sul viaggio in ItaliaMoncalieri, )
  • Some current publications 
    Aercke, Kristiaan P. G.
  • Samarcande, 1400-1500 
    SAS; 199529020; English; Aercke, Kristiaan; kaercke@lau.edu.lb; Lebanese American University (Editions AutrementParis, )
  • HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche 
    Georgess, Dan; Xian, Lingling; Huso, Tait; Cope, Leslie; Belton, Amy; Chang, Yu-ting
    High-mobility group A1 (Hmga1) chromatin remodelling proteins are enriched in intestinal stem cells (ISCs), although their function in this setting was unknown. Prior studies showed that Hmga1 drives hyperproliferation, ...
  • Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin 
    Georgess, Dan; Harre, Ulrike; Bang, Holger; Bozec, Aline; Axmann, Roland; Ossipova, Elena
    Autoimmunity is complicated by bone loss. In human rheumatoid arthritis (RA), the most severe inflammatory joint disease, autoantibodies against citrullinated proteins are among the strongest risk factors for bone destruction. ...
  • Molecular mechanisms implicated in bone resorption 
    Georgess, Dan (Ecole Normale Superieure de Lyon, )
    Bone remodeling is a physiological process by which old bone is replaced by new bone. Osteoclasts are multinucleated giant cells of the monocytic lineage. Their function is bone resorption, the first step of bone remodeling. ...
  • Anti-osteoclastic effects of C-glucosidic ellagitannins mediated by actin perturbation 
    Georgess, Dan; Spuul, Pirjo; Le Clainche, Christophe; Le Nihouannen, Damien; Fremaux, Isabelle; Dakhli, Thierry
    Actin subunits assemble into actin filaments whose dynamics and three-dimensional architectures are further regulated by a variety of cellular factors to establish the functional actin cytoskeleton. The C-glucosidic ...
  • mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation 
    Georgess, Dan; Asrani, Kaushal; Sood, Akshay; Torres, Alba; Phatak, Pornima; Kaur, Harmisar
    Despite its central position in oncogenic intracellular signaling networks, the role of mTORC1 in epithelial development has not been studied extensively in vivo. Here, we have used the epidermis as a model system to ...
  • Twist1-positive epithelial cells retain adhesive and proliferative capacity throughout dissemination 
    Georgess, Dan; Shamir, Eliah R.; Coutinho, Kester; Auer, Manfred; Elwald, Andrew J.
    Dissemination is the process by which cells detach and migrate away from a multicellular tissue. The epithelial-to-mesenchymal transition (EMT) conceptualizes dissemination in a stepwise fashion, with downregulation of ...
  • Mosaic loss of non-muscle myosin IIA and IIB is sufficient to induce mammary epithelial proliferation 
    Georgess, Dan; Nguyen-Ngoc, Kim-vy; Silvestri, Vanesa; Fairchild, Armanda N.; Ewald, Andrew J.
    The mammary epithelium elaborates through hormonally regulated changes in proliferation, migration and differentiation. Non-muscle myosin II (NMII) functions at the interface between contractility, adhesion and signal ...
  • Biphasic effects of vitamin D and FGF23 on human osteoclast biology 
    Georgess, Dan; Machuca-Gayet, Irma; Demoncheaux, Nathalie; Allard, Lise; Coury-Lucas, Fabienne; Jurdic, Pierre; Bacchetta, Justine
    Vitamin D and FGF23 play a major role in calcium/phosphate balance. Vitamin D may control bone resorption but the potential role of FGF23 has never been evaluated. The objective of this study was therefore to compare the ...
  • Podosome rings generate forces that drive saltatory osteoclast migration 
    Dan, Georgess; Hu, Shiqiong; Planus, Emmanuelle; Place, Christophe; Wang, Xianghui; Alibiges-Rizo, Corinne; Jurdic, Pierre; Geminard, Jean-Christophe; Mogliner, Alexander
    Podosomes are dynamic, actin-containing adhesion structures that collectively self-organize as rings. In this study, we first show by observing osteoclasts plated on bead-seeded soft substrates that podosome assemblies, ...
  • Comparative transcriptomics reveals RhoE as a novel regulator of actin dynamics in bone-resorbing osteoclasts 
    Georgess, Dan; Mazzorana, Marlene; Terrado, Jose; Delpart, Chrisitne; Chamot, Christophe; Guasch, Rosa M.; Perez-Roger, Ignocia; Jurdic, Pierre; Machuca-Gayet, Irma
    The function of osteoclasts (OCs), multinucleated giant cells (MGCs) of the monocytic lineage, is bone resorption. To resorb bone, OCs form podosomes. These are actin-rich adhesive structures that pattern into rings that ...
  • Podosome organization drives osteoclast-mediated bone resorption 
    Georgess, Dan; Machuca-Gayet, Irma; Blangy, Anne; Jurdic, Pierre
    Osteoclasts are the cells responsible for physiological bone resorption. A specific organization of their most prominent cytoskeletal structures, podosomes, is crucial for the degradation of mineralized bone matrix. Each ...
  • Transformation of journalistic labor and precarization 
    Uzunoglu, Sarphan; SAS; 201802117; Communication Arts; sarphan.uzunoglu@lau.edu.lb; Lebanese American University
    The crisis, known as the Dotcom bubble in the world, is recently occuring in Turkey’s new digital newsrooms. Due to uncertainty in news economy and recent developments in Turkey’s media industry, dozens of digital newsrooms ...
  • After a post-modern suicide 
    Uzunoglu, Sarphan
    On October 17th 2014, a man named Mehmet Pişkin uploaded his suicide note to the Vimeo in a video format. This video was automatically shared with his Facebook friends after he commited suicide. This occasion that effected ...
  • New media and new practices of exploitation 
    Uzunoglu, Sarphan
    Triple-C’s 2012 dated issue titled Marx is Back was involving a contemporary and critical analysis of the rise and institutionalization of neoliberalism in media industry. Furthermore, this analysis ...

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